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Thursday, February 16, 2012

Patients' views on participating in medical research - Part 1: Attitudes

While we are still working on our 'Funders' Policies on data sharing' article we decided to post here a summary of recent work on patients' attitudes to participating in medical research - again, a primer on the current state of play in clinical research in the UK selecting choice elements from recent reports; check out the footnotes for interesting sources to follow up. Part 2 will cover Engagement and Participation and will be followed by a piece on medics' attitudes to research. As always, let us know what you think - if there are more recent / complete / credible studies out there which draw different conclusions, let us know!

We also came across a tweet today from Simon Denegri linking via his blog to an NIHR site containing video testimonials of the experiences of patients, nurses and doctors taking part in or working on clinical trials which is worth a look too. Apologies for the bizarre formatting of the bullet-points below!


Attitudes

The following bullet points are extracted from the text of the report “The Use of Personal Health Information in Medical Research General Public Consultation” which presents the the findings of a programme of research carried out among the general public by Ipsos MORI on behalf of the Medical Research Council (MRC) published in July 2007 with the aim of “Identifying public concerns and misconceptions surrounding the secondary use of personal health information for medical research.”

In summary they found that there was low public awareness of medical research, that the public were in general supportive of research when informed about it and when they felt in control of their data – but continue to have reservations about privacy:

·         “The advantages of medical research are seen by the public to far outweigh the disadvantages. Seven in ten feel the merits of research outweigh the disadvantages, compared to only 6% who say the opposite.”

·         The qualitative phase of this consultation showed that there was little public awareness and understanding of medical research (and thus the use of secondary health information for medical research purposes), who undertakes it and to what ends.

·         “The workshops indicate that, if the public is informed about what medical research entails, they are generally positive towards it. Communications are key to building public trust… Key to effective communication on the subject is the need to keep terminology simple.”

·         The quantitative phase of the research showed that “Just over a third (34%) cannot think of any associations with the phrase personal health information, which indicates fairly low awareness for the MRC to address.”

·         “Perceptions of who, or which organisations people feel would hold personal health information focus mainly around the health service [GPs, hospital doctors and the NHS]. Medical researchers (working in any capacity) are mentioned by less than 1% of the general public.”

·         “If the public feels in control of their information and its potential uses, then they are likely to be more inclined to allow their personal health information to be used for medical research purposes…The qualitative research shows that the main public concerns are over organisations sharing this information, particularly for commercial gain…. Medical researchers working in the public sector i.e. for Government and universities (both trusted by 11%) are more trusted than their counterparts working for private companies (4%). The private sector features prominently among the least trusted organisations where personal health information is concerned.”

·         “While most see the benefit of personal health information being used for medical research purposes, the very same people can hold reservations over the implications for privacy…. The most common reason for being unlikely or certain not to allow personal health information to be used for medical research purposes is concern over privacy (28%).”

·         “The two key pillars of anonymity and consent feature highly in the debate over what information should be available, to whom, and in what circumstances. These two themes are central to building trust.”

·         “The vast majority (87%) trust GPs to have access to their personal health information, and over half trust other health professionals – such as consultants or hospital doctors (59%).”

·         The public needs “a human face to reassure them and discuss the issues around consent and confidentiality with them. Health professionals in general, and GPs in particular, are the most trusted to perform this role. For many, the GP’s surgery is the most frequent point of contact on health issues and it would seem sensible to use this as one location for dissemination of information about personal health information for medical research purposes.”[1]

The Academy of Medical Sciences presented a review of public engagement on the use of patient data, summarising several reports thus:

·         NHS Connecting for Health – Using patient information in the NHS (2009).98 This report found that the 96 participants were generally happy for their data to be used in research as long as anonymity was ensured and they were approached by someone they knew and trusted, such as their GP.

·         Royal Academy of Engineering –Young people’s views on the development and use of Electronic Patient Records (201099) Of 3,000 young people surveyed, most were not against the idea of anonymised data being used in medical research; 50% said that they would want to be asked for consent each time researchers used their anonymous record.

·         New Economics Foundation - Exploring public views on personal electronic health records (October 2010100) Surveyed 6000 people and found: that 57% of adults and 67% of young people were enthusiastic about the benefits of switching to digital patient records; and that patient consent would be essential for using identifiable data for research.

·         Wellcome Trust/University of Surrey – Public Attitudes to Research Governance (2006). Based on interviews and focus groups with 89 people; the report found participants were willing to provide personal data for biomedical research providing its use had been explained to them. Concerns remained over whether promises of anonymity and security could be fully relied on.

·         MRC/Ipsos MORI - The Use of Personal Health Information in Medical Research (2007). Interviewed a sample of 2,106 UK adults and found that 69% were ‘likely’ to allow the data to be used for health research purposes

·         Academy of Medical Sciences - Personal data for public good: using health information in medical research (2006). Consulted with a wide range of patient representatives and found research using personal data was strongly supported. Public engagement was identified as one of the most important tasks in developing future arrangements for appropriate governance for the use of health information in health research.[2]

Another 2007 report, a survey of literature covering public and professional attitudes to privacy of healthcare data commissioned by the General Medical Council and conducted by Cambridge Health Informatics, came to the following conclusions:
·         Assessment of public attitudes is dependent on how the topic is framed. People will express concerns if questioned about ‘concerns’, but will readily trade these ‘concerns’ for health  or other benefits, even altruistic ones.
·         ‘Real world’ choices can be very different (and constrained) from those offered in opinion surveys where costs and trade-offs may not appear.
·         Public attitudes are not uniform and the surveys suggest that they are often either ill-informed or unformed (or sometimes formed during an investigation or discussion).
·         Attitudes among the public vary from the completely unconcerned to a small proportion of the public that has strong views on privacy, either from a sense of a ‘right to privacy’ or because of some sensitive episode in the past that they wish to protect. The majority of the public seem to rely on trust in clinicians and the healthcare system.
·         It is clear that the public (and to some degree the professions) are unclear on the potential roles of medical records in modern healthcare.
·         The public would like a choice in the use of their records, but there is little hard evidence about what arrangement of choices the public would generally prefer – or whether there are radically different opinions on this.
·         The public appear to be becoming more comfortable with computer technology, which may reduce fears over privacy, but with increasing expectations over security and choice about access to their records.[3]
Of note these authors contend that “Generally much of healthcare policy in relation to the privacy of healthcare data has been based on historic ethical and legal considerations together with financial practicalities rather than on an evidence-base of what individuals would want or expect.  This has been, in part, been due to a perceived lack of understanding by the public at large (and many professionals too) of how medical records are actually used and shared within the healthcare system as a whole: this perception means that they have rarely been asked in any formal consultative way.”
They also contend, however, that “Establishing public concerns about the privacy of health data poses problems because, from the few surveys that have been performed, it appears that only a small proportion of the public have a strong opinion and fewer still have an understanding of the complex issues that need to be weighed up when arriving at an opinion.”[4]


[1] Ipsos MORI on behalf of the Medical Research Council: The Use of Personal Health Information in Medical Research General Public Consultation [2007]
[2] Ibid. Full citations for these reports are:
UK Clinical Research Collaboration (2010). Attitudes and awareness amongst General Practioners (GPs) and
patients about the use of patient data in research – a study by the UK Clinical Research Collaboration Board
Sub-Group on Public Awareness. UCKRC, London.
NHS Connecting for Health (2009). Using patient information in the NHS.
http://www.connectingforhealth.nhs.uk/engagement/public/consultations/hsreport.pdf
Royal Academy of Engineering (2010).Privacy and prejudice: young people’s views on the development and
use of electronic patient records.
http://www.raeng.org.uk/news/publications/list/reports/Privacy_and_Prejudice_EPR_views.pdf
New Economics Foundation (2010). Who sees what? Exploring public views on personal electronic health
records.
http://www.neweconomics.org/sites/neweconomics.org/files/Who_Sees_What.pdf
Wellcome Trust/University of Surrey (2006) Public attitudes to research governance: a qualitative study in a
deliberative context.
http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document
/wtx038443.pdf
Medical Research Council/Ipsos MORI (2007). The use of personal health information in medical research.
http://www.mrc.ac.uk/consumption/idcplg?IdcService=GET_FILE&dID=10983&dDocName=MRC003810&allowI
nterrupt=1
Academy of Medical Sciences (2006). Personal data for public good: using health information in medical
research. http://www.acmedsci.ac.uk/download.php?file=/images/publication/Personal.pdf
[3] Cambridge Health Informatics report for the General Medical Council: Public and Professional attitudes to privacy of healthcare data - A Survey of the Literature; http://www.gmc-uk.org/GMC_Privacy_Attitudes_Final_Report_with_Addendum.pdf_27007284.pdf
[4] Cambridge Health Informatics report for the General Medical Council: Public and Professional attitudes to privacy of healthcare data - A Survey of the Literature; http://www.gmc-uk.org/GMC_Privacy_Attitudes_Final_Report_with_Addendum.pdf_27007284.pdf

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